Comparison of oral midazolam as a premedication in children to oral midazolam combined with ketamine

• MV Reddy

  English

  Author

Ketamine and midazolam are frequently utilized as premedicants in pediatric patients. The effectiveness
of oral midazolam vs the combination of midazolam and ketamine as premedicants in a pediatric age range
of sixty children was examined in this prospective randomized research. The study comprised 30 patients
in each group, ages 2–6, receiving major and intermediate surgery. Group A got oral midazolam (0.5
mg/kg) forty-five minutes before surgery, while group B received oral ketamine (3 mg/kg) and midazolam
(0.25 mg/kg) in the recovery room.
Sedation onset, emotional response, sedation score, intravenous cannulation response, and acceptance of
the face mask were among the observations. The unpaired t-test and the chi-square test were used to
analyze the data. Compared to the midazolam group alone, the outcomes shown in the midazolam and
ketamine group were statistically significant. 

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