PLGA Microspheres' Association with Carrier Pellets by Fluid Bed Coating: An Innovative Method for Increasing Microparticle Flowability

• KH Yang

  English

  Author

• HT Peng

  English

  Author

Because of their potential biopharmaceutical benefits, micro- and nanoparticles have been investigated as
possible oral drug delivery methods. These systems may improve drug absorption [1] and regulate drug
release [2] according to their granulometric profiles and chemical compositions. Additionally, the micro-
and nanoencapsulation of bioactive substances may result in an overall improvement in medication stability
[3, 4]. However, because of their small particle size, these systems have significant technical restrictions
that result in decreased flowability in the solid state. Managing and processing such tiny particles could
turn into a significant industrial issue because of their compromised mechanical qualities [5], which affects
the viability and cost of manufacture.

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