Remotely Activated Scaffolds for Managed Drug Release

• D Vishnyakova

  English

  Author

Fe3O4-Au hybrid nanoparticles (HNPs) have shown growing promise for biomedical uses,
including medication delivery that responds to image-guided stimuli. Future biological applications might
greatly benefit from incorporating the special qualities of HNPs into thermally sensitive scaffolds. Here,
we effectively created thermoresponsive poly(N-isopropylacrylamide) (pNiPAM)-based smart scaffolds.
When exposed to a brief laser burst, nanoparticles that provide a localized heating trigger were discovered
to enable remote control of bulk polymer shrinkage. Wet chemical precipitation techniques were used to
create gold-covered iron oxide nanoparticles, which were then electrochemically coated.

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